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Regulatory mechanisms of human and mouse telomerase reverse transcriptase gene transcription: distinct dependency on c-Myc

Telomerase—a complex ribonucleoprotein enzyme—synthesizes telomeric repeats to avoid telomere loss that accompanies cell division and chromosomal replication. Expression of telomerase is detectable in embryonic cells and cancer cells, but not in normal human cells. On the other hand, in mice, substa...

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Bibliografische gegevens
Hoofdauteurs: Fujiki, Tsukasa, Udono, Miyako, Kadooka, Keishi, Yamashita, Shuntaro, Miura, Takumi, Shirahata, Sanetaka, Katakura, Yoshinori
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Netherlands 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978306/
https://ncbi.nlm.nih.gov/pubmed/20454928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9276-y
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