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Regulatory mechanisms of human and mouse telomerase reverse transcriptase gene transcription: distinct dependency on c-Myc
Telomerase—a complex ribonucleoprotein enzyme—synthesizes telomeric repeats to avoid telomere loss that accompanies cell division and chromosomal replication. Expression of telomerase is detectable in embryonic cells and cancer cells, but not in normal human cells. On the other hand, in mice, substa...
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| Hoofdauteurs: | , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Springer Netherlands
2010
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978306/ https://ncbi.nlm.nih.gov/pubmed/20454928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10616-010-9276-y |
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