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Patch-clamp amplifiers on a chip

We present the first, fully-integrated, two-channel implementation of a patch-clamp measurement system. With this “PatchChip” two simultaneous whole-cell recordings can be obtained with rms noise of 8 pA in a 10 kHz bandwidth. The capacitance and series-resistance of the electrode can be compensated...

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Detalhes bibliográficos
Main Authors: Weerakoon, Pujitha, Culurciello, Eugenio, Yang, Youshan, Santos-Sacchi, Joseph, Kindlmann, Peter J., Sigworth, Fred J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978236/
https://ncbi.nlm.nih.gov/pubmed/20637803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2010.06.030
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