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Pre-Clinical Drug Prioritization via Prognosis-Guided Genetic Interaction Networks
The high rates of failure in oncology drug clinical trials highlight the problems of using pre-clinical data to predict the clinical effects of drugs. Patient population heterogeneity and unpredictable physiology complicate pre-clinical cancer modeling efforts. We hypothesize that gene networks asso...
Gorde:
| Egile Nagusiak: | , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Public Library of Science
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978107/ https://ncbi.nlm.nih.gov/pubmed/21085674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013937 |
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