Phosphoproteomics-Based Modeling Defines the Regulatory Mechanism Underlying Aberrant EGFR Signaling

BACKGROUND: Mutation of the epidermal growth factor receptor (EGFR) results in a discordant cell signaling, leading to the development of various diseases. However, the mechanism underlying the alteration of downstream signaling due to such mutation has not yet been completely understood at the syst...

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Main Authors:	Tasaki, Shinya, Nagasaki, Masao, Kozuka-Hata, Hiroko, Semba, Kentaro, Gotoh, Noriko, Hattori, Seisuke, Inoue, Jun-ichiro, Yamamoto, Tadashi, Miyano, Satoru, Sugano, Sumio, Oyama, Masaaki
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science 2010
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2978091/ https://ncbi.nlm.nih.gov/pubmed/21085658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013926
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Phosphoproteomics-Based Modeling Defines the Regulatory Mechanism Underlying Aberrant EGFR Signaling

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