Phosphoproteomics-Based Modeling Defines the Regulatory Mechanism Underlying Aberrant EGFR Signaling

BACKGROUND: Mutation of the epidermal growth factor receptor (EGFR) results in a discordant cell signaling, leading to the development of various diseases. However, the mechanism underlying the alteration of downstream signaling due to such mutation has not yet been completely understood at the syst...

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Main Authors: Tasaki, Shinya, Nagasaki, Masao, Kozuka-Hata, Hiroko, Semba, Kentaro, Gotoh, Noriko, Hattori, Seisuke, Inoue, Jun-ichiro, Yamamoto, Tadashi, Miyano, Satoru, Sugano, Sumio, Oyama, Masaaki
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2978091/
https://ncbi.nlm.nih.gov/pubmed/21085658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0013926
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