Impact of ETIF Deletion on Safety and Immunogenicity of Equine Herpesvirus Type 1-Vectored Vaccines

Heterologous gene transfer by viral vector systems is often limited by factors such as preexisting immunity, toxicity, low packaging capacity, or weak immunogenic potential. A novel viral vector system derived from equine herpesvirus type 1 (EHV-1) not only overcomes some of these obstacles but also...

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Detalhes bibliográficos
Main Authors: Hofmann-Sieber, Helga, Wild, Jens, Fiedler, Nicole, Tischer, Karsten, von Einem, Jens, Osterrieder, Nikolaus, Hofmann, Heike, Köstler, Josef, Wagner, Ralf
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977905/
https://ncbi.nlm.nih.gov/pubmed/20826695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00677-10
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