Virally Induced Cellular MicroRNA miR-155 Plays a Key Role in B-Cell Immortalization by Epstein-Barr Virus

Infection of resting primary human B cells by Epstein-Barr virus (EBV) results in their transformation into indefinitely proliferating lymphoblastoid cell lines (LCLs). LCL formation serves as a model for lymphomagenesis, and LCLs are phenotypically similar to EBV-positive diffuse large B-cell lymph...

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Detaylı Bibliyografya
Asıl Yazarlar: Linnstaedt, Sarah D., Gottwein, Eva, Skalsky, Rebecca L., Luftig, Micah A., Cullen, Bryan R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology (ASM) 2010
Konular:
Transformation and Oncogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977875/
https://ncbi.nlm.nih.gov/pubmed/20844043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01248-10
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