Template supercoiling during ATP-dependent DNA helix tracking: studies with simian virus 40 large tumor antigen.

Incubation of topologically relaxed plasmid DNA with simian virus 40 (SV40) large tumor antigen (T antigen), ATP, and eubacterial DNA topoisomerase I resulted in the formation of highly positively supercoiled DNA. Eukaryotic DNA topoisomerase I could not substitute for eubacterial DNA topoisomerase...

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Bibliographic Details
Main Authors: Yang, L, Jessee, C B, Lau, K, Zhang, H, Liu, L F
Format: Artigo
Language:Inglês
Published: 1989
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC297787/
https://ncbi.nlm.nih.gov/pubmed/2548199
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