Role of N-Linked Glycans in the Functions of Hepatitis C Virus Envelope Proteins Incorporated into Infectious Virions

Hepatitis C virus (HCV) envelope glycoproteins are highly glycosylated, with generally 4 and 11 N-linked glycans on E1 and E2, respectively. Studies using mutated recombinant HCV envelope glycoproteins incorporated into retroviral pseudoparticles (HCVpp) suggest that some glycans play a role in prot...

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Bibliographische Detailangaben
Hauptverfasser: Helle, François, Vieyres, Gabrielle, Elkrief, Laure, Popescu, Costin-Ioan, Wychowski, Czeslaw, Descamps, Véronique, Castelain, Sandrine, Roingeard, Philippe, Duverlie, Gilles, Dubuisson, Jean
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Structure and Assembly
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2977866/
https://ncbi.nlm.nih.gov/pubmed/20844034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01548-10
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