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Stimulation of phosphorylation of lipocortin at threonine residues by epidermal growth factor (EGF) and the EGF receptor: addition of protein kinase P with polylysine inhibits this effect.

In this paper we show that epidermal growth factor (EGF) stimulates the phosphorylation of lipocortin 1, at threonine as well as at tyrosine residues, by a highly purified preparation of the EGF receptor. The phosphorylation of threonine residues is catalyzed by an enzyme that contaminates the recep...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Abdel-Ghany, M, Kole, H K, el Saad, M A, Racker, E
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1989
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297777/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548197/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.16.6072
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