Tumor necrosis factor alpha activates human immunodeficiency virus type 1 through induction of nuclear factor binding to the NF-kappa B sites in the long terminal repeat.

Expression of human immunodeficiency virus type 1 (HIV-1) can be activated in a chronically infected T-cell line (ACH2 cells) by a cytokine, human tumor necrosis factor alpha (TNF-alpha). TNF-alpha treatment of ACH2 cells resulted in an increase in steady-state levels of HIV RNA and HIV transcriptio...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Duh, E J, Maury, W J, Folks, T M, Fauci, A S, Rabson, A B
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297754/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2762307/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5974
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