Phorbol 12-myristate 13-acetate inhibits binding of leukotriene B4 and platelet-activating factor and the responses they induce in neutrophils: site of action.

The addition of the platelet-activating factor (PAF) to neutrophils causes an increase in cytoskeletal actin, a rise in the intracellular concentration of free calcium, release of arachidonic acid, and the synthesis of PAF. The PAF synthesis in human neutrophils stimulated by PAF is greatly potentia...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Yamazaki, M, Gomez-Cambronero, J, Durstin, M, Molski, T F, Becker, E L, Sha'afi, R I
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297716/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548188/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5791
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