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Predicting the orientation of eukaryotic membrane-spanning proteins.

We have developed a rule to predict the orientation of the first internal signal-anchor sequence in eukaryotic transmembrane proteins synthesized on the rough endoplasmic reticulum. The difference in the charges of the 15 residues flanking the first internal signal-anchor determines its orientation,...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hartmann, E, Rapoport, T A, Lodish, H F
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1989
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC297715/
https://ncbi.nlm.nih.gov/pubmed/2762295
Tagiau: Ychwanegu Tag
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