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Predicting the orientation of eukaryotic membrane-spanning proteins.
We have developed a rule to predict the orientation of the first internal signal-anchor sequence in eukaryotic transmembrane proteins synthesized on the rough endoplasmic reticulum. The difference in the charges of the 15 residues flanking the first internal signal-anchor determines its orientation,...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297715/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2762295/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5786 |
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