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Autoregulatory control of beta-tubulin mRNA stability is linked to translation elongation.

Tubulin synthesis in animal cells is controlled in part by an autoregulatory mechanism that modulates the stability of ribosome-bound tubulin mRNAs. For beta tubulin, the initial recognition event for this selective RNA instability has previously been shown to be a cotranslational binding (presumabl...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Gay, D A, Sisodia, S S, Cleveland, D W
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297710/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2762294/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5763
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