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The Use of ß-Cyclodextrin in the Manufacturing of Disintegrating Pellets with Improved Dissolution Performances

It has recently been highlighted that the release behavior of pellets containing microcystalline cellulose (MCC) as the spheronizing agent may be impaired by the lack of disintegration. Although alternative spheronizing excipients have been proposed, their overall advantages have not thoroughly been...

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Autors principals: Zema, Lucia, Palugan, Luca, Maroni, Alessandra, Foppoli, Anastasia, Sangalli, Maria Edvige, Gazzaniga, Andrea
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976967/
https://ncbi.nlm.nih.gov/pubmed/18523889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9106-0
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