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Transmembrane signaling by a chimera of the Escherichia coli aspartate receptor and the human insulin receptor.

Since many receptors apparently contain only one or two membrane-spanning segments, their transmembrane topology should be similar. This feature suggests that these receptors share common mechanisms of transmembrane signaling. To test the degree of conservation of signaling properties, a chimeric re...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Moe, G R, Bollag, G E, Koshland, D E
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297694/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2548185/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.15.5683
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