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Solubility Improvement of Drugs using N-Methyl Pyrrolidone
The solubilization efficiency of N-methyl pyrrolidone (NMP) has been determined and compared to that of ethanol and propylene glycol for 13 poorly soluble drugs. NMP is found to be a more efficient solubilizer for all the drugs studied. The solubility enhancement as high as about 800-fold is obtaine...
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| Huvudupphovsmän: | , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Springer US
2008
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976935/ https://ncbi.nlm.nih.gov/pubmed/18431671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9050-z |
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