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Design and Evaluation of Self-Emulsifying Drug Delivery Systems (SEDDS) of Nimodipine

The ability of self-emulsifying drug delivery systems (SEDDS) to improve solubility, dissolution rate and bioavailability of a poorly water-soluble calcium channel blocker, nimodipine (NM) was evaluated in the present investigation. Solubility of NM in various oils, surfactants and cosurfactants was...

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Detalhes bibliográficos
Main Authors: Kale, Amit A., Patravale, Vandana B.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976914/
https://ncbi.nlm.nih.gov/pubmed/18446481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-008-9037-9
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