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Design and Evaluation of Self-Microemulsifying Drug Delivery System (SMEDDS) of Tacrolimus
The objective of present investigation was to formulate self-microemulsifying drug delivery systems (SMEDDS) of tacrolimus (FK 506), a poorly water soluble immunosuppressant that exhibits low and erratic bioavailability. Solubility of FK 506 in various oils, surfactants cosurfactants and buffers was...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Springer US
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976874/ https://ncbi.nlm.nih.gov/pubmed/18446456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-007-9014-8 |
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