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Restoration of myelin formation by a single type of myelin basic protein in transgenic shiverer mice.
A minigene containing mouse cDNA coding for the smallest type of myelin basic protein and including the native promoter was constructed and used to produce transgenic shiverer mice. The hypomyelinating mouse, the shiverer, has a deletion in its myelin basic protein gene, lacks all four types of myel...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1989
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297684/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2473474/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5661 |
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