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Binding site and ligand flexibility revealed by high resolution crystal structures of GluK1 competitive antagonists
The availability of crystal structures for the ligand binding domains of ionotropic glutamate receptors, combined with their key role in synaptic function in the normal and diseased brain, offers a unique selection of targets for pharmaceutical research compared to other drug targets for which the a...
में बचाया:
| मुख्य लेखकों: | , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2976827/ https://ncbi.nlm.nih.gov/pubmed/20558186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2010.06.002 |
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