Germline Variation in Apoptosis Pathway Genes and Risk of non-Hodgkin Lymphoma

BACKGROUND: The t(14;18)(q32;q21) is the most commonly observed chromosomal translocation in non-Hodgkin lymphoma (NHL), resulting in constitutive Bcl-2 expression and apoptosis inhibition. In addition, germline variation in both BCL2L11 (BIM) and CASP9, known regulators of apoptosis, have recently...

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Главные авторы: Kelly, Jennifer L., Novak, Anne J., Fredericksen, Zachary S., Liebow, Mark, Ansell, Stephen M., Dogan, Ahmet, Wang, Alice H., Witzig, Thomas E., Call, Timothy G., Kay, Neil E., Habermann, Thomas M., Slager, Susan L., Cerhan, James R.
Формат: Artigo
Язык:Inglês
Опубликовано: 2010
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976783/
https://ncbi.nlm.nih.gov/pubmed/20855536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-10-0581
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