Monoclonal antibody against interferon gamma can prevent experimental cerebral malaria and its associated overproduction of tumor necrosis factor.

Experimental cerebral malaria (ECM), a lethal hyperacute neurological syndrome associated with high blood levels of tumor necrosis factor, develops in genetically susceptible (CBA/Ca) mice 7 days after infection with Plasmodium berghei ANKA strain. Injections of neutralizing monoclonal antibody agai...

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Bibliographic Details
Main Authors: Grau, G E, Heremans, H, Piguet, P F, Pointaire, P, Lambert, P H, Billiau, A, Vassalli, P
Format: Artigo
Language:Inglês
Published: 1989
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC297664/
https://ncbi.nlm.nih.gov/pubmed/2501793
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