The tick saliva immunosuppressor, Salp15, contributes to Th17-induced pathology during Experimental Autoimmune Encephalomyelitis

Salp15 is a tick saliva protein that inhibits CD4(+) T cell differentiation through its interaction with CD4. The protein inhibits early signaling events during T cell activation and IL-2 production. Because murine experimental autoimmune encephalomyelitis development is mediated by central nervous...

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Main Authors: Juncadella, Ignacio J., Bates, Tonya C., Suleiman, Reem, Monteagudo-Mera, Andrea, Olson, Chris M., Navasa, Nicolás, Olivera, Elias R., Osborne, Barbara A., Anguita, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976633/
https://ncbi.nlm.nih.gov/pubmed/20920474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2010.09.125
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