Interleukin 3 activates human blood basophils via high-affinity binding sites.

Pure populations of human basophilic granulocytes were obtained from chronic myeloid leukemia (CML) blood by negative selection using a mixture of monoclonal antibodies and complement. 125I-radiolabeled recombinant human interleukin 3 (rhIL-3) bound to purified basophils in a specific manner. Quanti...

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Bibliographic Details

Published in:	Proc Natl Acad Sci U S A
Main Authors:	Valent, P, Besemer, J, Muhm, M, Majdic, O, Lechner, K, Bettelheim, P
Format:	Artigo
Language:	Inglês
Published:	National Academy of Sciences 1989
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297659/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2473472/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5542
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