Sin Resolvase Catalytic Activity and Oligomerization State are Tightly Coupled

Serine recombinases promote specific DNA rearrangements by a "cut and paste" mechanism which involves cleavage of all four DNA strands at two sites recognized by the enzyme. Dissecting the order and timing of these cleavage events and the steps leading up to them is difficult because the c...

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Autores principales: Mouw, Kent W., Steiner, Andrew M., Ghirlando, Rodolfo, Li, Nan-Sheng, Rowland, Sally-J., Boocock, Martin R., Stark, W. Marshall, Piccirilli, Joseph A., Rice, Phoebe A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976518/
https://ncbi.nlm.nih.gov/pubmed/20868695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.08.057
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