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Molecular analysis of the human beta-globin locus activation region.

Recently, DNA sequences containing four erythroid-specific DNase I hypersensitive sites within 20 kilobases 5' of the human epsilon-globin gene have been identified as an important cis-acting regulatory element, the locus activation region (LAR). Subfragments of the LAR, containing either all or onl...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Forrester, W C, Novak, U, Gelinas, R, Groudine, M
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1989
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297638/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2748594/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5439
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