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Toll-Like Receptor 2 Deficiency Results in Impaired Antibody Responses and Septic Shock during Borrelia hermsii Infection

Overwhelming bacteremia is a leading cause of death. To understand the mechanisms involved in protective antibody and pathological inflammatory responses during bacteremia, we have been studying the murine model of Borrelia hermsii infection. Toll-like receptor (TLR) signaling plays an important rol...

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Autors principals: Dickinson, Gregory S., Piccone, Heather, Sun, Guizhi, Lien, Egil, Gatto, Louis, Alugupalli, Kishore R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976319/
https://ncbi.nlm.nih.gov/pubmed/20696824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00438-10
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