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Klf5 regulates lineage formation in the pre-implantation mouse embryo

Kruppel-like transcription factors (Klfs) are essential for the induction and maintenance of pluripotency of embryonic stem cells (ESCs), yet little is known about their roles in establishing the three lineages of the pre-implantation embryo. Here, we show that Klf5 is required for the formation of...

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Autori principali: Lin, Suh-Chin J., Wani, Maqsood A., Whitsett, Jeffrey A., Wells, James M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Company of Biologists 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976279/
https://ncbi.nlm.nih.gov/pubmed/20980403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.054775
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