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Novel Activity of Rhodobacter sphaeroides Spheroidene Monooxygenase CrtA Expressed in Escherichia coli

The spheroidene monooxygenase CrtA of Rhodobacter sphaeroides introduces a keto group and/or hydroxy group at the ends of nonnative substrates in Escherichia coli, resulting in the production of novel oxocarotenoids. The heme-containing CrtA is not a P450 enzyme but a new type of oxygenase.

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Bibliografiske detaljer
Main Authors: Lee, Pyung Cheon, Holtzapple, Erik, Schmidt-Dannert, Claudia
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976243/
https://ncbi.nlm.nih.gov/pubmed/20851979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.01606-10
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