Low Frequency of Intermittent HIV-1 Semen Excretion in Patients Treated with Darunavir-Ritonavir at 600/100 Milligrams Twice a Day plus Two Nucleoside Reverse Transcriptase Inhibitors or Monotherapy

HIV-1 RNA level and darunavir concentration in the genital tract were measured in 45 men receiving darunavir-ritonavir mono- or tritherapy. At week 48, a low frequency (3/45) of HIV-1 RNA shedding was observed in patients (1 on monotherapy and 2 on triple therapy), although they had undetectable HIV...

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Hauptverfasser: Lambert-Niclot, Sidonie, Peytavin, Gilles, Duvivier, Claudine, Poirot, Catherine, Algarte-Genin, Michèle, Pakianather, Sophie, Meynard, Jean-Luc, Valantin, Marc-Antoine, Molina, Jean-Michel, Flandre, Philippe, Katlama, Christine, Calvez, Vincent, Marcelin, Anne-Geneviève
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Antiviral Agents
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976146/
https://ncbi.nlm.nih.gov/pubmed/20713677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00725-10
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