Population Pharmacokinetics and Pharmacodynamics of Artemether and Lumefantrine during Combination Treatment in Children with Uncomplicated Falciparum Malaria in Tanzania

The combination of artemether (ARM) and lumefantrine is currently the first-line treatment of uncomplicated falciparum malaria in mainland Tanzania. While the exposure to lumefantrine has been associated with the probability of adequate clinical and parasitological cure, increasing exposure to artem...

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Main Authors: Hietala, Sofia Friberg, Mårtensson, Andreas, Ngasala, Billy, Dahlström, Sabina, Lindegårdh, Niklas, Annerberg, Anna, Premji, Zul, Färnert, Anna, Gil, Pedro, Björkman, Anders, Ashton, Michael
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
Assuntos:
Pharmacology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976134/
https://ncbi.nlm.nih.gov/pubmed/20713675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00252-10
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