A Heterologous MF59-Adjuvanted H5N1 Prepandemic Influenza Booster Vaccine Induces a Robust, Cross-Reactive Immune Response in Adults and the Elderly

Immunogenicity and safety of a booster dose of an MF59-adjuvanted H5N1 vaccine containing 7.5 μg A/turkey/Turkey/1/2005-like (clade 2.2) H5N1 hemagglutinin, given approximately 18 months after primary vaccination with a heterologous strain, were evaluated. The booster vaccine was well tolerated and...

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Detalhes bibliográficos
Main Authors: Fragapane, Elena, Gasparini, Roberto, Schioppa, Francesco, Laghi-Pasini, Franco, Montomoli, Emanuele, Banzhoff, Angelika
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976095/
https://ncbi.nlm.nih.gov/pubmed/20810680
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00461-09
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