Common variants at ten loci modulate the QT interval duration in the QTSCD Study

The QT interval, a measure of cardiac repolarization, predisposes to ventricular arrhythmias and sudden cardiac death (SCD) when prolonged or shortened. A common variant in NOS1AP is known to influence repolarization. We analyze genome-wide data from five population-based cohorts (ARIC, KORA, SardiN...

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Autori principali: Pfeufer, Arne, Sanna, Serena, Arking, Dan E, Müller, Martina, Gateva, Vesela, Fuchsberger, Christian, Ehret, Georg B, Orrú, Marco, Pattaro, Cristian, Köttgen, Anna, Perz, Siegfried, Usala, Gianluca, Barbalic, Maja, Li, Man, Pütz, Benno, Scuteri, Angelo, Prineas, Ronald J, Sinner, Moritz F, Gieger, Christian, Najjar, Samer S, Kao, W H Linda, Mühleisen, Thomas W, Dei, Mariano, Happle, Christine, Möhlenkamp, Stefan, Crisponi, Laura, Erbel, Raimund, Jöckel, Karl-Heinz, Naitza, Silvia, Steinbeck, Gerhard, Marroni, Fabio, Hicks, Andrew A, Lakatta, Edward, Müller-Myhsok, Bertram, Pramstaller, Peter P, Wichmann, H-Erich, Schlessinger, David, Boerwinkle, Eric, Meitinger, Thomas, Uda, Manuela, Coresh, Josef, Kääb, Stefan, Abecasis, Gonçalo R, Chakravarti, Aravinda
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976045/
https://ncbi.nlm.nih.gov/pubmed/19305409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.362
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