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The role of the K(ATP) channel in glucose homeostasis in health and disease: more than meets the islet

ATP-sensitive potassium (K(ATP)) channels are critical for the maintenance of glucose homeostasis. They are essential for glucose-stimulated insulin secretion from pancreatic β-cells, contribute to the mechanisms by which hypoglycaemia stimulates glucagon release from pancreatic α-cells, and are inv...

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Main Authors: McTaggart, James S, Clark, Rebecca H, Ashcroft, Frances M
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2976015/
https://ncbi.nlm.nih.gov/pubmed/20519313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2010.191767
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