PLATELET-ACTIVATING FACTOR AND HYPERACUTE REJECTION: THE EFFECT OF A PLATELET-ACTIVATING FACTOR ANTAGONIST, SRI 63-441, ON REJECTION OF XENOGRAFTS AND ALLOGRAFTS IN SENSITIZED HOSTS

The pathogenesis of hyperacute transplantation reactions includes the activation of a cascade of nonspecific inflammatory reactions that precipitates the destruction of the target organ. Platelet-activating factor (PAF) represents an important component of these inflammatory cascades, and we have ex...

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Main Authors: Makowka, Leonard, Chapman, Frances A., Cramer, Donald V., Qian, Shiguang, Sun, Hong, Starzl, Thomas E.
Format: Artigo
Language:Inglês
Published: 1990
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975976/
https://ncbi.nlm.nih.gov/pubmed/2402783
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