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Labeling the peptidyltransferase center of the Escherichia coli ribosome with photoreactive tRNA(Phe) derivatives containing azidoadenosine at the 3' end of the acceptor arm: a model of the tRNA-ribosome complex.

Photoreactive derivatives of yeast tRNA(Phe) containing 2-azidoadenosine (2N3A) at position 73 or 76 have been crosslinked to the peptidyl site of Escherichia coli ribosomes. Covalent tRNA-ribosome attachment was dependent upon the replacement of adenosine by 2N3A in the tRNA, irradiation with 300-n...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Wower, J, Hixson, S S, Zimmermann, R A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1989
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297595/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2664777/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5232
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