Identification of a monocyte specific pre-interleukin 1 beta convertase activity.

Interleukin 1 (IL-1) is a lymphokine secreted by monocytes in response to a variety of inflammatory stimuli. IL-1 beta, the predominant form of IL-1 produced by human monocytes, is synthesized as an inactive precursor of 31 kDa and is cleaved at Asp116-Ala117 to yield a 17.5-kDa extracellular form....

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Kostura, M J, Tocci, M J, Limjuco, G, Chin, J, Cameron, P, Hillman, A G, Chartrain, N A, Schmidt, J A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297594/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2787508/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.14.5227
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