Identification of a monocyte specific pre-interleukin 1 beta convertase activity.

Interleukin 1 (IL-1) is a lymphokine secreted by monocytes in response to a variety of inflammatory stimuli. IL-1 beta, the predominant form of IL-1 produced by human monocytes, is synthesized as an inactive precursor of 31 kDa and is cleaved at Asp116-Ala117 to yield a 17.5-kDa extracellular form....

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Bibliografiska uppgifter
Huvudupphovsmän: Kostura, M J, Tocci, M J, Limjuco, G, Chin, J, Cameron, P, Hillman, A G, Chartrain, N A, Schmidt, J A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1989
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC297594/
https://ncbi.nlm.nih.gov/pubmed/2787508
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