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Corruption of phage-display libraries by target-unrelated clones: Diagnosis and countermeasures

Phage display is used to discover peptides or proteins with a desired target property—most often, affinity for a target selector molecule. Libraries of phage clones displaying diverse surface peptides are subject to a selection process designed to enrich for the target behavior, and subsequently pro...

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Detalhes bibliográficos
Main Authors: Thomas, William D., Golomb, Miriam, Smith, George P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975937/
https://ncbi.nlm.nih.gov/pubmed/20692225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2010.07.037
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