Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease

A low level of HDL-C is the most common plasma lipid abnormality observed in men with established coronary heart disease (CHD). To identify allelic variants associated with susceptibility to low HDL-C and CHD, we examined 60 candidate genes with key roles in HDL metabolism, insulin resistance, and i...

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Détails bibliographiques
Auteurs principaux: Peloso, Gina M., Demissie, Serkalem, Collins, Dorothea, Mirel, Daniel B., Gabriel, Stacey B., Cupples, L. Adrienne, Robins, Sander J., Schaefer, Ernst J., Brousseau, Margaret E.
Format: Artigo
Langue:Inglês
Publié: The American Society for Biochemistry and Molecular Biology 2010
Sujets:
Patient-Oriented and Epidemiological Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975725/
https://ncbi.nlm.nih.gov/pubmed/20855565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.P008268
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