Susceptibility to rheumatoid arthritis maps to a T-cell epitope shared by the HLA-Dw4 DR beta-1 chain and the Epstein-Barr virus glycoprotein gp110.

Rheumatoid arthritis is associated with the HLA antigen HLA-DR4. Disease susceptibility maps to the amino acid sequence QKRAA located in the third hypervariable region of the DR beta-1 chain. This region is thought to be a site of recognition for the T-cell antigen receptor. We searched for an antig...

Полное описание

Библиографические подробности

Опубликовано в::	Proc Natl Acad Sci U S A
Главные авторы:	Roudier, J, Petersen, J, Rhodes, G H, Luka, J, Carson, D A
Формат:	Artigo
Язык:	Inglês
Опубликовано:	National Academy of Sciences 1989
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297565/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2472638/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5104
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