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Positive selection of a T-cell subpopulation in the thymus in which it develops.

In SWR mice the expression with high-density V beta 17a (high V beta 17a) of the T-cell antigen receptors correlates with the CD4+8- subpopulation of thymocytes. By contrast, in thymocytes of SJL mice the expression of high V beta 17a is observed on the CD4+8- or CD4-8+ subpopulation. However, when...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Iwabuchi, K, Negishi, I, Arase, H, Iwabuchi, C, Ogasawara, K, Good, R A, Onoé, K
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297562/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2500662/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5089
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