Positive selection of a T-cell subpopulation in the thymus in which it develops.

In SWR mice the expression with high-density V beta 17a (high V beta 17a) of the T-cell antigen receptors correlates with the CD4+8- subpopulation of thymocytes. By contrast, in thymocytes of SJL mice the expression of high V beta 17a is observed on the CD4+8- or CD4-8+ subpopulation. However, when...

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Publicado en:	Proc Natl Acad Sci U S A
Autores principales:	Iwabuchi, K, Negishi, I, Arase, H, Iwabuchi, C, Ogasawara, K, Good, R A, Onoé, K
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	National Academy of Sciences 1989
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297562/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2500662/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.5089
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