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Portacaval shunt causes apoptosis and liver atrophy in rats despite increases in endogenous levels of major hepatic growth factors

BACKGROUND/AIMS: The response to the liver damage caused by portacaval shunt (PCS) is characterized by low-grade hyperplasia and atrophy. To clarify mechanisms of this dissociation, we correlated the expression of ‘hepatotrophic factors’ and the antihepatotrophic and proapoptotic peptide, transformi...

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Detalhes bibliográficos
Main Authors: Gandhi, Chandrashekhar R., Murase, Noriko, Subbotin, Vladimir M., Uemura, Tadahiro, Nalesnik, Michael, Demetris, Anthony J., Fung, John J., Starzl, Thomas E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975525/
https://ncbi.nlm.nih.gov/pubmed/12175629
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