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Corticotropin positively regulates its own receptors and cAMP response in cultured bovine adrenal cells.

Bovine fasciculata adrenal cells contain specific high-affinity (KD approximately 2.3 +/- 0.4 x 10(-10) M) and low-capacity (1910 +/- 300 sites per cell) corticotropin (ACTH) receptors. Pretreatment of cells with ACTH, caused in a time-(maximum effect at 48 hr) and dose-(ED50 approximately 10(-11) M...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Penhoat, A, Jaillard, C, Saez, J M
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1989
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297539/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2544885/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.4978
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