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Slc35c2 Promotes Notch1 Fucosylation and Is Required for Optimal Notch Signaling in Mammalian Cells

Mammalian Notch receptors require modification by fucose on epidermal growth factor-like (EGF) repeats of their extracellular domain to respond optimally to signal induction by canonical Notch ligands. Inactivation of the Golgi GDP-fucose transporter Slc35c1 in mouse or human does not cause marked d...

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Bibliografske podrobnosti
Main Authors: Lu, Linchao, Hou, Xinghua, Shi, Shaolin, Körner, Christian, Stanley, Pamela
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975247/
https://ncbi.nlm.nih.gov/pubmed/20837470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.126003
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