Identification of Acidic pH-dependent Ligands of Pentameric C-reactive Protein

C-reactive protein (CRP) is a phylogenetically conserved protein; in humans, it is present in the plasma and at sites of inflammation. At physiological pH, native pentameric CRP exhibits calcium-dependent binding specificity for phosphocholine. In this study, we determined the binding specificities...

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Main Authors: Hammond, David J., Singh, Sanjay K., Thompson, James A., Beeler, Bradley W., Rusiñol, Antonio E., Pangburn, Michael K., Potempa, Lawrence A., Agrawal, Alok
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975246/
https://ncbi.nlm.nih.gov/pubmed/20843812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.142026
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