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Mixed spermatogenic germ cell nuclear extracts exhibit high base excision repair activity

Spermatogenic cells exhibit a lower spontaneous mutation frequency than somatic tissues in a lacI transgene and many base excision repair (BER) genes display the highest observed level of expression in the testis. In this study, uracil-DNA glycosylase-initiated BER activity was measured in nuclear e...

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Autori principali: Intano, Gabriel W., McMahan, C. Alex, Walter, Ronald B., McCarrey, John R., Walter, Christi A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC29752/
https://ncbi.nlm.nih.gov/pubmed/11239003
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