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Ethanol-induced HO-1 and NQO1 Are Differentially Regulated by HIF-1α and Nrf2 to Attenuate Inflammatory Cytokine Expression

Oxidative stress plays an important role in alcohol-induced inflammation and liver injury. Relatively less is known about how Kupffer cells respond to oxidative stress-induced expression of heme oxygenase-1 (HO-1) and NAD(P)H:quinone oxidoreductase (NQO1) to blunt inflammation and liver injury. We s...

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Detalhes bibliográficos
Main Authors: Yeligar, Samantha M., Machida, Keigo, Kalra, Vijay K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975160/
https://ncbi.nlm.nih.gov/pubmed/20833713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.138636
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