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cAMP stimulates transcription of the beta 2-adrenergic receptor gene in response to short-term agonist exposure.

In addition to conveying cellular responses to an effector molecule, receptors are often themselves regulated by their effectors. We have demonstrated that epinephrine modulates both the rate of transcription of the beta 2-adrenergic receptor (beta 2AR) gene and the steady-state level of beta 2AR mR...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Collins, S, Bouvier, M, Bolanowski, M A, Caron, M G, Lefkowitz, R J
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1989
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC297513/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2472635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.13.4853
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