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No evidence for dualism in function and receptors: PD-L2/B7-DC is an inhibitory regulator of human T cell activation
The B7 family member programmed-death-1-ligand 2 (PD-L2/B7-DC) is a ligand for programmed-death-receptor 1 (PD-1), a receptor involved in negative regulation of T cell activation. Several independent studies have reported that PD-L2 can however also potently costimulate murine T cells via an additio...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975063/ https://ncbi.nlm.nih.gov/pubmed/16598819 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200535344 |
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