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Ranolazine Attenuates Behavioral Signs of Neuropathic Pain
Ranolazine modulates the cardiac voltage-gated sodium channel (Na(v) 1.5) and is FDA-approved for the treatment of ischemic heart disease. Ranolazine also targets neuronal (Na(v) 1.7, 1.8) isoforms that are implicated in neuropathic pain. Therefore, we determined the analgesic efficacy of ranolazine...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2975014/ https://ncbi.nlm.nih.gov/pubmed/19773645 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e3283323c90 |
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