Ranolazine Attenuates Behavioral Signs of Neuropathic Pain

Ranolazine modulates the cardiac voltage-gated sodium channel (Na(v) 1.5) and is FDA-approved for the treatment of ischemic heart disease. Ranolazine also targets neuronal (Na(v) 1.7, 1.8) isoforms that are implicated in neuropathic pain. Therefore, we determined the analgesic efficacy of ranolazine...

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Bibliografiske detaljer
Main Authors: Gould, Harry J., Garrett, Colleen, Donahue, Renee R., Paul, Dennis, Diamond, Ivan, Taylor, Bradley K.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2975014/
https://ncbi.nlm.nih.gov/pubmed/19773645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/FBP.0b013e3283323c90
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